Easy Cattle Drive Casserole

Cattle Drive Casserole with cheesy layers on a rustic plate, showing seasoned ground beef, fluffy biscuit base, and melted cheddar cheese.

Easy Cattle Drive Casserole

This Cattle Drive Casserole is a hearty, family-style dinner made with a biscuit base, seasoned ground beef, and a creamy cheesy topping. It is a comforting recipe perfect for busy nights and sweet kitchen memories in under an hour.

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Course: Dinner

Cuisine: American

Keyword: biscuit base casserole, Cattle Drive Casserole, Cowboy Casserole, family casserole recipe, Tex Mex dinner

Prep Time: 20

Cook Time: 35

Total Time: 55

Servings: servings

Calories: 520kcal

Cost: $18

Equipment

9×13-inch baking dish Use a deep dish so the layers bake evenly without spilling
Large Skillet
Medium mixing bowl
Small mixing bowl
Wooden spoon or spatula

Ingredients

Biscuit Base

2 cups Bisquick baking mix Red Lobster Cheddar Bay biscuit mix works beautifully too
0.67 cup milk
1 cup shredded cheddar cheese

Beef Layer

2 lb ground beef 80/20 works best for flavor
1 medium onion diced
1 packet taco seasoning about 1 ounce
1 can diced tomatoes with green chiles 10 ounces, do not drain
1 can black beans 15 ounces, drained and rinsed
1 cup frozen corn
to taste salt and black pepper

Topping

1 cup sour cream
0.5 cup mayonnaise
2 cups shredded cheddar cheese divided
1 cup shredded Monterey Jack cheese

Instructions

Preheat the oven to 350°F (175°C) and lightly grease a 9x13-inch baking dish.
In a medium bowl, mix the Bisquick baking mix, milk, and shredded cheddar cheese. Spread evenly into the bottom of the prepared baking dish.
In a large skillet, cook the ground beef and onion over medium-high heat until browned. Drain excess grease.
Stir in the taco seasoning with a little water, then add diced tomatoes with green chiles, black beans, and corn. Simmer a few minutes.
Spread the beef mixture evenly over the biscuit base.
In a small bowl, mix the sour cream and mayonnaise until smooth. Spread gently over the beef layer.
Sprinkle 1 cup of cheddar cheese and all of the Monterey Jack cheese over the top.
Bake for 30–35 minutes until bubbly and golden. Sprinkle remaining cheddar during the last 5 minutes. Rest 5 minutes before serving.

Notes

You can swap the Bisquick for Red Lobster Cheddar Bay biscuit mix for a richer flavor.
Cornbread mix also works if you want a more Southern-style casserole.
Leftovers keep well in the fridge for up to 3 days and reheat beautifully.
This casserole is perfect for potlucks, busy weeknights, and those evenings when you just want everyone around the table.

Nutrition